Shai Gilgeous-Alexander leads the 2025-26 guard rankings as the safest fantasy anchor due to elite scoring, assists and defensive stats plus rare durability. Luka Doncic lands right behind, now in a Lakers setup built to maximize playmaking and spacing. The list spotlights Cade Cunningham’s continued ascent, Anthony Edwards and Devin Booker as high-ceiling scorers, and a tier of versatile guards (Morant, Mitchell, Curry, Harden) with varying risk profiles. Rookie-leaning breakouts (Amen Thompson, Quickley) and veterans adjusting to new rosters (VanVleet, Poole) shape late-round upside, while availability and injury risk remain the currency of drafts.