Keon Coleman has flashed big-play upside for Buffalo in 2025, posting Week 1 numbers that underscored his role as Josh Allen’s premier deep threat. A quieter Week 2 tempered expectations, but Thursday’s date with the Dolphins could unleash another boom game if Buffalo leans on the passing attack. Coleman remains a high-end WR3/Flex in 10-12 team leagues, offering weekly upside when the Bills air it out.

Miami’s defense has bent but not broken on WRs early, so Coleman’s ceiling hinges on volume and red-zone looks. If Buffalo pushes the ball downfield to chase points, Coleman could again hit double-digit targets and multiple big plays, making him a compelling fantasy option in the right matchups.

Week 3 on Thursday Night Football surfaces with a Miami Dolphins plan without Darren Waller, who is chasing a late NFL comeback but sidelined by a hip injury after a trade from the Giants. Waller missed practice and is listed as out, forcing Miami to lean on other targets as Bills-weak defense pressure grows. Fantasy managers should watch for his return timeline and opponent-adjusted plays, while the offense adapts around Hill, Waddle, and in-two-TE looks as the weeks unfold.

Beyond Waller, the NFL news cycle spins through Patrick Mahomes’ rushing milestone, Derrick Henry’s high school stats, and Tom Brady’s controversy, painting a broader canvas of players and pivots shaping weekly fantasy and betting decisions. The blend of injury news, comeback stories, and historical moments primes rosters for strategic week-to-week moves.

Week 3 fantasy starts hinge on injury updates and high-volume targets. Jauan Jennings’ ankle status could push Ricky Pearsall into a larger role, while Tetairoa McMillan continues as Carolina’s top target with a robust Week 2 workload. Jaylen Warren’s pass-game involvement points to solid RB2 production, and DK Metcalf is a buy-low candidate with tangible upside as Pittsburgh filters in more passes. The piece highlights the Who Should I Start tool to optimize four-player comparisons and unlock precise, matchup-driven decisions for Week 3.

Expect a mix of floor versus ceiling in Week 3: McMillan and Pearsall offer reliable targets, Jennings’ status dictates Cardinals-upside, and Metcalf represents a pivotal buy-low anchor as the Steelers chase offensive consistency. The analysis threads through each listed player—Jennings, Moore, McMillan, Dobbins, Warren, Pearsall, Smith, Swift, Meyers, Metcalf—clarifying who should start, who could disappoint, and where upside hides in Week 3 matchups.

Week 3 brings Seattle as 7.5-point favorites at home against New Orleans, but injuries to Devon Witherspoon and Nick Emmanwori could blunt Seattle’s secondary edge. Spencer Rattler and the Saints offense have found traction, and the SportsLine model assigns a 38% upset chance for New Orleans—a surprisingly credible figure for a road test. The model’s Week 3 survivor pick diverges from Seattle, suggesting a one-score outcome with Seattle at about 62% win probability.

The slate features seven 5+ point spreads, including Dolphins-Bills, Packers-Browns, Falcons-Panthers, Jets-Bucs, Saints-Seahawks, Chiefs-Giants, and Lions-Ravens, underscoring how survivor players will chase value. The model touts a long, earned track record (10,000 simulations, 37-17 on top picks since 2024) and is the guiding beacon for those locking Week 3 picks, with promos noted for new users.