Chicago Bears host Buffalo Bills in a primetime tune‑up where the projected starters are set to push into action, including Caleb Williams, as Chicago aims to gauge performance in a live setting after joint practices. The spotlight shifts to cohesion on offense—Williams working with Rome Odunze—plus an extended look at Colston Loveland and the revamped offensive line anchored by Drew Dalman. On defense, the Bears push their edge with Dayo Odeyingbo and Montez Sweat flanking Gervon Dexter as Tremaine Edmunds roams the middle.

As Chicago tests run and pass, the Bills offer a stiff test to evaluate the new-look front and the young core around Williams’ progress. Fans seeking fantasy signals should monitor early snap counts, how quickly Williams gets the ball out, and which pass‑catchers emerge alongside Odunze and Loveland.