Ravens’ late-game deficits and Bills’ relentless aggression define the week’s takeaway: Baltimore’s ability to win big games remains undeniable, yet clutch moments and clock-management have repeatedly betrayed them. Buffalo’s grit—driving drives on fourth down and keeping Josh Allen in a high-variance, high-output mode—demonstrates how nuanced play-calling can tilt tight games. Fantasy managers should lean into dual-threats and playmakers who can deliver in crunch time, especially in pass-friendly matchups.

Lamar Jackson’s rushing upside continues to anchor fantasy value, while Mark Andrews and Zay Flowers emerge as reliable targets in high-leverage moments. On the other side, Josh Allen’s ceiling remains towering, with Dawson Knox and Diggs providing stabilized targets when the Bills lean into quick throws and quarterback creativity. Zack-by-zay timing and breakout runs shape who to trust in upcoming weeks.

For broader fantasy planning, the Chargers’ offense looks promising with Justin Herbert and Quinton Johnson, while Tyreek Hill and Tua Tagovailoa remain volatile but explosive in the right setup. Daniel Jones’ late bloom in Week 1 signals safer streaming options in New York. In all, injuries and game flow will decide who becomes must-starts as the season unfolds.

Openers also spotlight Jaylen Carter’s impact, Cowboys’ offensive line potential, and the Chiefs’ evolving approach under Spagnolo. The league’s best teams still feel unshakeable, but strategic depth—especially at quarterback and the pass-catching corps—will determine fantasy outcomes week-to-week.