Kansas City’s preseason setback vs Seattle left five Chiefs with injuries, including Felix Anudike-Uzomah and rookie Nohl Williams. Coach Andy Reid stressed injuries are common in August, but Week 1 against the Chargers in Sao Paulo approach adds urgency to return timelines. The Chiefs also noted veterans Jack Cochrane and Nazeeh Johnson among the shaken players, with Mike Edwards in the mix as a veteran depth piece. This injure list tightens KC’s defensive rotation and could shift snap counts early as they aim to field a full-strength unit for Week 1.

Fantasy window shifts as Chiefs’ rookies and depth players could see upticks if starters miss time. Anudike-Uzomah’s health matters for KC’s edge pressure, while Johnson and Cochrane factor into the secondary’s depth chart. The Seahawks game provided a reminder of the physical grind in August, and the Week 1 Brazil tilt against the Chargers looms as the real test. Stakeholders should monitor official updates closely as rosters settle postgame, with prized defensive plays potentially hinging on health.

In sum, Kansas City’s immediate concern is preserving top-shelf players for the season opener; depth players may carry early-season fantasy value, especially if injuries linger into September.