George Karlaftis leans into Brazilian jiu-jitsu to sharpen leverage and hand-fighting for the Chiefs’ pass rush. As a blue belt training under Master Dave Smarr, he pairs 6 a.m. sessions with Tamba Hali and Joe Kim to translate grappling into edge-rush technique.

He signed a four-year, $93 million extension after leading KC with eight sacks in 2024, and his unit is framed alongside Trent McDuffie, Isiah Pacheco and Bryan Cook as a college of players chasing another deep playoff run with cross‑training potentially boosting fantasy upside.

Kansas City finalizes its 53-man roster, trimming 29 players, with a clear aim to keep the Chiefs lean at quarterback and maximize upside across skill positions. The backfield blends Isiah Pacheco, Kareem Hunt, Elijah Mitchell, and Brashard Smith, while Rashee Rice headlines a WR group that also includes Hollywood Brown, Xavier Worthy, and JuJu Smith-Schuster. Travis Kelce anchors the tight end room alongside Noah Gray and Noah Wiley, with Robert Tonyan likely to rejoin. The o-line stays compact at nine, and the defense rotates around Karlaftis, Jones, Tillery, Nnadi, and Tranquill. Rice’s suspension timeline adds a wrinkle early, and waivers will shape the practice squad long before Week 1 in Brazil against the Chargers.

KC’s waiver strategy centers on re-signing potential practice-squad gems and the possibility of Tonyan returning as a veteran option. The roster also hints at how the Chiefs will deploy depth along the DL, LB, and secondary, especially with Nazeeh Johnson sidelined to start the first four games. The Chiefs’ Week 1 plan remains fluid, but the path to a strong fantasy season is anchored in Mahomes, Kelce, and a high-ceiling WR corps backed by a versatile backfield and a defense ready to lean on pressure from the edge and run-stopping interior.»

Felix Anudike-Uzomah landed on injured reserve with a hamstring strain, likely ending his 2025 season for the Kansas City Chiefs. The 23-year-old former first-round pick has 41 tackles, 8 tackles for loss, and 3 sacks in 34 games since 2023, but injuries and limited snaps in 2024-25 have clouded his development. KC now leans on George Karlaftis, Charles Omenihu, and rookie Ashton Gillotte to fill edge depth, potentially elevating Gillotte into a regular early-role pass rusher as the team weighs a fifth-year option for 2027.

The injury backdrop intersects with a wider Chiefs storyline: Rashee Rice has drawn NFL attention with a report that a double-digit game suspension was proposed for him, which could shift targets and game plans while Anudike-Uzomah is sidelined. Fantasy managers should monitor the defensive rotation and Gillotte’s snaps, as well as how KC’s edge pressure and run defense evolve without their top pending breakout option. The development adds urgency to KC’s long-term decisions and could tilt depth-chart bets for the rest of the season.