Chiefs and Chargers collide in Sao Paulo on neutral ground as Patrick Mahomes and KC seek to extend dominance after a 15-2 season, while LA leans on a passing attack led by Ladd McConkey in a test of KC’s defense. The SportsLine model flags the Under 45.5 with a value spread edge, fuelling DFS and betting talk for a Week 1 showcase with big-play potential.

Fantasy managers should watch Mahomes’ Week 1 history against the Chargers and McConkey’s breakout upside in a high-variance environment. Neutral-site drama can spark surprises, making this Brazil bout a prime pivot for both cash-game stability and tournament-wide upside.