Mac Jones is set to start for San Francisco after a knee scare, with Adrian Martinez not elevated. Eli Apple was added from the practice squad for Sundays game against Jacksonville, signaling confidence in the rest of the depth chart. Ricky Pearsall and Jauan Jennings are questionable but likely to play, keeping Bourne, Robinson, Valdes-Scantling and Skyy Moore as viable targets if one sits. Colby is questionable; Moss or Zakelj could step in. Brandon Aiyuk’s absence remains the defining storyline for the offense.

If Pearsall and Jennings sit, the 49ers would lean on a shallow WR corps; if one plays, expect a broader distribution with the expected nod to Bourne and the Chiefs pairing of Robinson, Valdes-Scantling and Moore. The 49ers will list inactives 90 minutes before kickoff at Levi’s Stadium.