Josh Simmons is out for Kansas City, and Jaylon Moore will start at left tackle with Wanya Morris in reserve. Mahomes has protected with a rotating blind side in five Super Bowls, and Moore’s first start this season adds urgency. Detroit’s secondary is decimated with four corners sidelined, though Kerby Joseph and Brian Branch are active. Taylor Decker is inactive for the Lions, amplifying concerns about pass protection. Inactives: Chiefs – Fulton, Wiley, Mitchell, Herring; Lions – Arnold, Maddox, Decker, Vaki, Cunningham, Wingo, Strickland.

The matchup hinges on Chiefs' approach to slow down Detroit’s depleted secondary and Lions’ ability to pressure Mahomes despite injuries. Fantasy angles point to Chiefs pass-catchers benefiting from quicker reads and possible red-zone opportunities, while Detroit could lean on run-heavy looks and opportunistic defense if the Chiefs protect selectively.

Jawaan Taylor handled a knee issue but logged full participation, keeping him on track for Week 6 against Detroit on Sunday Night Football. No game designation was given, suggesting he’s likely set to start at right tackle.

If Taylor can’t go, Wanya Morris or Jaylon Moore would step in, altering protection and run-blocking dynamics. Fantasy owners should watch practice updates closely to gauge Week 6 upside and the Chiefs’ edge protection plan.

Kansas City’s Week 3 clash with New York hinges on Josh Simmons’ illness status. He progressed to full participation after being limited earlier in the week and is expected to start at left tackle on Sunday Night Football, stabilizing KC’s front for Mahomes and the run game.

Wanya Morris and Jaylon Moore are ready to step in if needed, reinforcing the Chiefs’ depth on the line. This scenario matters for fantasy managers tracking KC’s blocking efficiency, snap distribution, and how protections against a stout Giants pass rush could tilt upside in the Chiefs’ skill-position output.