James Cook’s four-year, 48 million extension with 30 million guaranteed locks in Buffalo’s backfield plan and signals a true three-down role if he stays healthy. His college mileage was light, and his receiving efficiency last year hints at a premium fantasy path if the Bills lean into him in the air as well as on early downs.

Across the AFC, Browns’ quarterback competition and a rocky development process cloud Cleveland’s fantasy ceiling, even as Shadur Sanders showcases potential. Miami’s Chop Robinson left practice with an ankle/oblique issue, dampening the defense’s upside amid injuries, depth questions and an unsettled pass rush. In New England, Drake Maye carries tantalizing upside as Will Campbell anchors the line; early-week lines point to a Patriots offense capable of surprises, but fantasy value hinges on how quickly the rookies and new pieces gel. Track target distribution, depth-chart shifts, and injury news as preseason turns to Week 1 projections.