Week 2 pivots for fantasy rosters center on Jauan Jennings, Baker Mayfield, Chase Brown, Malik Nabers, De'Von Achane, Rashid Shaheed, Geno Smith, Brock Bowers, Calvin Austin III, and Amon-Ra St. Brown. Jennings' Week 2 status hinges on Kittle’s absence, boosting his target floor if active. Mayfield remains a mid-range QB1 in a pass-heavy setup as Tampa Bay leans through the air. Brown, Nabers, and Achane carry upside in high-scoring games; Shaheed stays a boom-bust option; Smith, Bowers, Austin III, and St. Brown anchor rosters with solid floors.

Defenses and matchups in Week 2 shape starts across the board. The Who Should I Start tool highlights four-player comparisons to optimize lineups, with injury status, volume, and schedule as key inputs. The overall guidance leans into upside where the schedule allows, while preserving safe floors for standard and PPR formats.