The Week 3 NFL preseason slate centers on volume plays and backfield churn, with starters resting and rostering leaning toward backups who can pile up yards and scoring opportunities. Tampa Bay’s offense looms large against a Bills unit missing its starters, while Arizona and LA’s depth charts offer similar upside as rosters sort themselves out. Clayton Tune is highlighted for a three-quarter workload, Trask is poised to push the TB offense, and Raheim Sanders should command meaningful touches for the Chargers. Skyy Moore and Trey Palmer present tournament spark, Theo Wease Jr. and Travis Vokolek bring affordable volume, and the field shifts toward cheap, high-uptick targets in these rosters.

In this guide, the emphasis is on coalitions and crews that can deliver fantasy value despite the absence of stars. Expect heavy quarterback and backfield volumes, with stacking and game-scripting decisions driving most lineup builds. The slate rewards risk with upside—especially in Tampa Bay, Arizona, and LA—where backups can deliver week-winner scores if opportunities unfold as projected.

As lineup decisions unfold, remember that a few pivot props—like a Tampa Bay stack paired with Williams or Palmer, or a Tune or Ewers-driven Dolphins stack—could separate winners from the field. This slate rewards execution on low-cost, high-usage players who can reach the end zone in extended drives.