Buffalo rode James Cook’s 132-yard, 2-TD eruption to a 30-10 win over the Jets, lifting them to 2-0. Miami slipped to 0-2 after a Week 2 loss in a divisional clash and a rough opener at Indianapolis. The series edge tilts toward Buffalo since 1980, with Josh Allen posting big numbers in 15 meetings. Achane has surfaced for Miami with 86 rushing yards and 11 catches in two games. Buffalo’s defense hints at upside with Joey Bosa forcing three fumbles and contributing pressure early.

Fantasy takeaways center on Cook’s workload, Achane’s evolving role, and the QB duel between Allen and Tagovailoa. Bills aim to keep Buffalo’s 30-point ceiling intact, while Miami searches for consistent offensive flow and cleaner execution against a high-rhanded defense. Ed Oliver’s absence shapes Bills’ interior depth as Trubisky crafts a surprising stat-line note in the backdrop of a competitive AFC East.