Luke McCaffrey is Christian McCaffrey’s younger brother and Ed McCaffrey’s son. A 2024 third-round pick by Washington, he’s emerged as the Commanders’ top kick-returner in 2025 and has 7 catches for 146 yards and 2 touchdowns through five games. Christian leads the family with a heavy workload for the 49ers, totaling 780 yards from scrimmage, while Luke’s path from Nebraska quarterback to Rice wide receiver highlights a versatile fantasy upside. The brothers have yet to meet in an NFL game, and Washington vs. San Francisco hasn’t occurred in 2024–25.