In the latest DraftKings strategy guide, pitching options are highlighted for the 12-game main slate, focusing on matchups that could yield the highest fantasy points. Among the top picks, Kodai Senga stands out, even facing challenges at Coors Field, owing to the Rockies' high strikeout rate. Senga's impressive HR/9 of 0.81 indicates his potential to limit long balls.

Alternatives under $8,000 include Ben Brown, who offers great value, and Colton Gordon, who faces a struggling Guardians lineup. Team stacking strategies emphasize optimal matchups against struggling pitchers, with the Orioles, Mets, Royals, and Cardinals featuring as key targets. Players like Adley Rutschman and Juan Soto are positioned for big performances based on recent statistics against their respective opponents.