As the 2025 MLB season progresses into Week 12, savvy fantasy baseball managers are on the lookout for potential waiver-wire pickups to bolster their teams. This week, several hitters are highlighted based on their low roster percentages across major platforms like ESPN and Yahoo.

Among the top recommendations is Ryan O'Hearn (BAL), who holds eligibility at both first base and the outfield and is especially valuable this week with only one left-handed pitcher facing him in a favorable schedule. Nathaniel Lowe (WSH) is also a noteworthy pickup, having shown consistent performance despite a lower roster rate. Meanwhile, Miguel Vargas (CHW) continues to perplex fantasy managers by remaining under the 50% threshold, despite his evident potential backed by impressive APR metrics.

For deeper leagues, consider Otto Lopez (MIA) and Thairo Estrada (COL), both having favorable matchups that could yield substantial points. Lopez has been showing signs of form with three consecutive top-100 finishes, while Estrada's return from injury has him primed for production. The landscape on the waiver wire is dynamic, with players like Eric Wagaman (MIA), proving to be solid options for those in need of versatile hitters.

As fantasy baseball managers navigate the waiver wire in Week 10, several undervalued players have emerged as potential game-changers. Rhys Hoskins of the Milwaukee Brewers, with 47% rostered, has been a consistent performer, hitting .264 with nine homers and 35 RBIs while providing utility at first base. Jose Caballero from the Tampa Bay Rays, positioned as a leadoff hitter, is on track for over 50 steals this season and should be on every roster. Also on the rise is Brewers outfielder Sal Frelick, boasting a .393 batting average over the last week, with impressive speed and power metrics that make him a solid addition. Lourdes Gurriel Jr., quietly effective for the Arizona Diamondbacks, continues to deliver steady production, while Ryan O'Hearn of the Baltimore Orioles has become a reliable contributor amidst the team's injury struggles.

Week 10 of the 2025 fantasy baseball season offers a plethora of player transactions in reaction to recent performances. Top prospect Ryan O'Hearn for the Baltimore Orioles continues to shine, boasting an impressive .329 average with nine home runs. His recent .365 batting average in May makes him a must-add. Daniel Palencia, the Cubs' closer, is another standout with a 1.74 ERA, making him a valuable asset for saves. Lance McCullers Jr. shows promise after a stellar outing, while Adrian Houser's numbers suggest a potential sell-off strategy due to high hard-hit rates. Finally, Addison Barger of the Blue Jays has transformed into a top add, hitting .322 with significant power, making him a strong buy for many leagues.

Baltimore Orioles rookie Coby Mayo's first MLB RBI was far from routine. In his 22nd game, he scored Ryan O'Hearn with an RBI single in the fourth inning but found himself caught in a rundown as he attempted to advance to second base. The play escalated when Mayo shoved White Sox Lenyn Sosa, leading to a benches-clearing incident. Afterward, Mayo explained his actions, stating that he was trying to draw an interference call, a strategy that didn't pan out. His manager Tony Mansolino highlighted the rookie's instinct to seek contact, which ultimately backfired.

Despite the drama, Mayo remains a top-100 prospect and is celebrated for his potential power, yet he struggles offensively, with a .094 batting average. He has yet to record his first extra-base hit in the majors but has opportunities ahead in the Orioles' young lineup.

The MLB DFS landscape for May 31, 2025, presents a nine-game slate that looks promising for daily fantasy enthusiasts. Solid weather conditions are expected across most games, with minor rain concerns in Philadelphia and New York. Targeting pitchers like Sonny Gray, whose recent performances against a struggling Texas Rangers lineup make him a strong candidate, is crucial. Kodai Senga is also appealing, particularly against a Rockies team with a high strikeout rate. Value picks in the infield include Ryan O'Hearn and Brett Baty, both of whom are showing impressive offensive form. The Mets, Rays, and Orioles are highlighted as potential stacking options for maximizing scoring potential this slate.