The Chicago White Sox's struggles persisted as they faced the Seattle Mariners, losing 4-3 in 11 innings. Despite having numerous opportunities, they could only manage a dismal 1-for-17 with runners in scoring position. Manager Will Venable highlighted the team's poor situational hitting and defensive lapses, particularly a wild throw by third baseman Josh Rojas that allowed the Mariners to tie the game. The Sox did see homers from Michael A. Taylor and Brooks Baldwin, contributing to their eight home runs in the series.

With Chase Meidroth placed on the injured list due to a thumb injury, the White Sox called up Jacob Amaya to fill the gap. Lenyn Sosa had been showing promise with a hitting streak and power at the plate, but ended the game hitless. Meanwhile, Luis Robert Jr. achieved a milestone by stealing his 100th base in addition to hitting his 100th career home run, joining an elite group in White Sox history.