As Major League Baseball rolls into a packed schedule on May 26, 2025, avid bettors are gearing up for the optimal No Runs First Inning (NRFI) bets. Today’s matchups feature promising pitching duels, notably in Cleveland with Yoshinobu Yamamoto and Gavin Williams. Each has established strong records against the NRFI, making their clash a focal point for bettors.

The Yankees face the Angels, where Ryan Yarbrough's recent form adds another layer of intrigue to the NRFI betting market. Notably, the Twins and Rays matchup also stands out, given both teams' solid NRFI performances. With odds ranging from +100 to -140, careful monitoring of starting lineups and weather conditions will be crucial for bettors aiming for a clean sweep in NRFI markets.