Week 22 fantasy closer updates center on clear saves and opportunistic pickups. Dennis Santana locksthe Pirates’ ninth inning, turning in two saves and shrugging off a midseason stumble as his job looks safe for fantasy purposes. Jose A. Ferrer stepped in for Washington with three saves in four appearances, signaling a likely closer-by-committee trend at the Nationals down the stretch. Randy Rodriguez still carries upside in San Francisco, showing the ceiling for saves when the Giants can run his arc. Victor Vodnik has grabbed two saves in Colorado, offering a viable late-inning option in the Rockies bullpen.

Deeper-league intrigue runs through Reid Detmers in Los Angeles, JoJo Romero in St. Louis (alongside Riley O’Brien sharing ninth-inning duties), and Calvin Faucher in Miami as Anthony Bender’s season-ending tibia injury clears room for late-inning opportunities. Raisel Iglesias posted five saves on the week, a reminder that the closer role can swing fast. Hunter Gaddis and Tanner Scott emerge as hot-handed back-end options, while bullpen dynamics in Texas and Arizona intensify as teams chase late wins and playoff positioning.