On Thursday, May 22, 2025, fantasy baseball enthusiasts have a five-game slate in MLB DFS to consider, featuring key divisional matchups. AJ Smith-Shawver stands out as a top pitcher, having posted a 1.08 ERA in his previous starts, particularly excelling against the Nationals. Jack Flaherty and Carlos Rodriguez are also intriguing options, while value plays like Nick Allen can help balance lineups. Major hitters such as Jose Ramirez and Matt Olson are in great form, promising potential high returns this slate. Weather conditions in cities like Pittsburgh and Boston may impact game outcomes, making it crucial to monitor updates.