The Minnesota Twins faced a tough loss against the Houston Astros, falling 3-2 in a dramatic ninth inning. Joe Ryan delivered a commendable performance with seven innings pitched, allowing only two hits, but was overshadowed by the Astros' Hunter Brown, who dominated the Twins with 12 strikeouts. In the deciding inning, Jhoan Duran walked Christian Walker and surrendered crucial hits to Jake Myers and Cam Smith, sealing the Astros' victory and ending the Twins' winning streak against them.

Ryan's only errors came in the third inning when Yanier Diaz hit a home run, putting the Astros up by two. The Twins tied it up later by Brooks Lee's homer off Brown, but ultimately couldn't secure the win. This loss not only extended the Twins' current losing streak to three games but also marked the Astros' clinching of the season series against Minnesota for the first time since 2022.