The MLB DFS landscape opens up significantly for Friday with 12 games starting at 7:05 p.m. ET, providing ample choices for lineup construction. Top pitching options include Kevin Gausman from the Toronto Blue Jays, who has shown improved metrics this season, and Jose Quintana from the Milwaukee Brewers, who despite a recent rough outing against a strong Cubs offense, is a solid choice against a struggling Tampa lineup.

Offensive stars to consider feature Mookie Betts and Juan Soto, both of whom have demonstrated high OPS against opposing pitchers. Betts, despite a slow start, is expected to rebound, especially against Eduardo Rodriguez, while Soto is reminding everyone of his elite hitting prowess with a recent surge. For budget-friendly picks, Josh Naylor has been productive for Arizona, and Mickey Moniak is benefiting from Coors Field's hitter-friendly atmosphere.

Stacking strategies include targeting matchups against struggling pitchers like Osvaldo Bido from the Athletics, alongside top hitters from the Yankees and Padres, notably Aaron Judge and Manny Machado, respectively. Both batters are primed for big games given their current forms and favorable matchups.

As the 2025 fantasy baseball season progresses, savvy players are on the lookout for pitchers showing surprising starts. Jake Irvin of the Washington Nationals has recently made waves, posting a dominant performance against the Mets with a 1.31 ERA in his last three starts. However, despite his curveball success, his reliance on weaker fastballs raises concerns about sustainability.

Meanwhile, Simeon Woods Richardson of the Minnesota Twins has also shown improvement, limiting the Angels to just one run in a recent outing. His increased curveball usage looks promising, yet a lack of whiffs suggests he may not be a reliable fantasy asset. Lastly, veteran Jose Quintana of the Milwaukee Brewers has been impressive with a 1.14 ERA, though his sinker-heavy approach and inability to generate strikeouts could limit his fantasy appeal.

The New York Mets are currently leading the MLB Power Rankings thanks to a stellar starting rotation with a league-leading 2.36 ERA, despite facing tough competition from teams like the Washington Nationals. Tylor Megill has emerged as a standout with a remarkable 1.74 ERA, proving crucial to the Mets' success.

The Los Angeles Dodgers remain a formidable opponent but are battling injury issues, particularly with Blake Snell and Tyler Glasnow. Meanwhile, the San Francisco Giants have skyrocketed up the rankings due to a series of thrilling walk-off wins. In contrast, the San Diego Padres, who previously held the top spot, have struggled recently, losing four straight.

Notable performances include Eugenio Suárez's historic four-home-run game, placing him among an exclusive group of players. José Quintana has also been impressive with a 1.14 ERA, leading the Milwaukee Brewers to significant early-season success.

As the MLB season heats up, Week 5 presents a host of players riding impressive hot streaks, but discerning which to buy or sell is crucial for fantasy managers. Jose Quintana of the Milwaukee Brewers has shown promise with a 1.14 ERA, but underlying metrics suggest he might be due for a downturn, making him a candidate for selling. In contrast, Austin Hays of the Cincinnati Reds is on fire with a .388 average, making him a prime pickup. Jorge Polanco of the Mariners and rookie Agustin Ramirez of the Marlins have made strong cases for roster spots with solid performances, while Noelvi Marte's resurgence after struggles adds depth to fantasy rosters.

As the 2025 MLB season enters Week 5, several players are making headlines with impressive performances. Jose Quintana of the Milwaukee Brewers has shown early promise with a 1.14 ERA, but given his expected batting average against, he may not be a reliable long-term option and is recommended as a sell. In contrast, Austin Hays from the Cincinnati Reds is on fire, boasting a .388 batting average with five homers, making him a strong buy. Jorge Polanco of the Seattle Mariners is also contributing significantly, hitting .377 with seven home runs, suggesting he's worth picking up. The Miami Marlins' Agustin Ramirez has made a splash in his debut, while Noelvi Marte from the Reds is reclaiming his prospect status with a strong showing. With these insights, fantasy managers must stay proactive on the waiver wire.