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Go To Full MLB Digest
September 12, 2025
MLB DFS Lineup Picks for Friday Action
@rotowire
RotoWire
MLB DFS Lineup Picks for Friday Action

Friday’s MLB DFS slate centers on value and upside across 12 games, led by Dylan Cease’s favorable Coors-to-Padres arc and Luis Gil rounding into form for New York. Martin Perez is a salary-conscious pivot in Cleveland, while Nick Kurtz stands out as the weekend’s elite power rookie target. Randy Arozarena profiles as a main-event upside play against Yusei Kikuchi, and Ramon Laureano’s split-heavy profile adds flexible outfield/OF3 options. Reds’ mini-stack (De La Cruz, Friedl, Lux) and Brewers’ trio (Chourio, Turang, Frelick) offer salary relief with upside against weaker matchups. Royce Lewis is heating up at home, Brandon Pfaadt’s road ERA remains a caveat, and Brandon Pfaadt’s road woes make him a risky one-off. The article also spots J.T. Ginn’s tough home assignment for Reds at Athletics, and Pallante’s hard contact allowed to lefties fuels Chourio’s bloom into 20/20 season territory.

Which Friday night DFS play stands out as the best value across SPs and which hitter should you stack around him?Which hitter provides the best combination of price and upside in Friday’s Top Targets?Is Arozarena a must-play against Kikuchi on Friday or should you diversify?Which Brewers players pair best with Chourio in this slate’s builds?
Mentions:
@Dylan Cease | San Diego Padres | MLB
@Dylan Cease | San Diego Padres | MLB
@Jackson Chourio | Milwaukee Brewers | MLB
@Jackson Chourio | Milwaukee Brewers | MLB
@Luis Gil | New York Yankees | MLB
@Luis Gil | New York Yankees | MLB
@Nick Kurtz | Cincinnati Reds | MLB
@Nick Kurtz | Cincinnati Reds | MLB
@Randy Arozarena | Tampa Bay Rays | MLB
@Randy Arozarena | Tampa Bay Rays | MLB
@Yusei Kikuchi | Toronto Blue Jays | MLB
@Yusei Kikuchi | Toronto Blue Jays | MLB

https://www.rotowire.com/baseball/article/mlb-dfs-..

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