As the MLB season progresses, Wednesday's action is set to provide an intriguing slate of games, perfect for daily fantasy sports (DFS) enthusiasts. With seven matchups commencing after 6:45 p.m. EDT, careful lineup construction is essential.

When selecting pitchers, JP Sears (OAK) is a strong choice against the struggling Angels. With a 3.31 ERA, he performs better on the road than at home. Randy Vasquez (SDP) presents a risky option against the Blue Jays, despite his respectable 3.45 ERA.

Looking at offensive stacks, the Phillies at Coors Field against Carson Palmquist should be prioritized. Trea Turner and J.T. Realmuto offer potential upside, particularly given Palmquist’s inexperience and the favorable hitting conditions. Another strong stack comes from the Braves against Trevor Williams, focusing on left-handed hitters like Matt Olson and Ozzie Albies, who have shown the ability to exploit Williams' vulnerability to lefties.