Today's MLB slate offers promising No Runs First Inning (NRFI) betting opportunities across five matchups, highlighting intriguing pitcher performances and batting trends. Notably, Zack Wheeler of the Philadelphia Phillies boasts an impressive 14-2 NRFI record, facing a struggling San Diego Padres lineup that has seen ten consecutive NRFIs.

In contrast, the Cincinnati Reds and Boston Red Sox matchup features Chase Burns, fresh from a strong debut, against Garrett Crochet, with the Red Sox's offense struggling significantly. The odds favor an NRFI, given Cincinnati's recent offensive stats against left-handers.

Similarly, the Athletics at Tampa Bay Rays looks ripe for an NRFI wager, especially with Jacob Lopez's dominant recent form and the Rays' fluctuating offensive performance. Meanwhile, the matchup between the Baltimore Orioles and Texas Rangers also suggests NRFI potential, with both pitchers coming off solid outings. Lastly, Michael Wacha of the Kansas City Royals remains undefeated in NRFI bets, facing a cooling Seattle Mariners lineup.