On June 16, 2025, the San Diego Padres and Los Angeles Dodgers are set to clash at Dodger Stadium, featuring Dylan Cease and Shohei Ohtani as the starting pitchers. Ohtani, making his first start since August 2023, will take the mound as an opener, with uncertain pitch count expectations. The Dodgers, currently leading the NL West, have won 4 of their last 5 home games against divisional rivals. Meanwhile, the Padres have shown resilience on the road, covering the spread in 4 out of their last 5 games.

Betting insights reveal the total runs for this matchup is set at 9.0, with NBC Sports Bet favoring the Dodgers on the moneyline while leaning towards a spread play on the Padres. Both teams have pivotal star players that could greatly influence the outcome tonight.