On April 27, 2025, every MLB team is set to take the field, providing ample opportunities for home run prop bets. Among the top players to watch are Kerry Carpenter of the Detroit Tigers, who faces a struggling Dean Kremer, and Lawrence Butler of the Oakland Athletics, who has shown consistent power. Brandon Lowe of the Tampa Bay Rays is also highlighted, with an enticing matchup against Randy Vasquez, making him a strong candidate for a home run. Another key name is Fernando Tatis Jr., who continues to shine for the San Diego Padres. Lastly, Teoscar Hernandez of the L.A. Dodgers is expected to capitalize on favorable matchups.