The Washington Nationals (33-47) faced the San Diego Padres (43-36) on June 25, 2025, with MacKenzie Gore starting for Washington against San Diego's Nick Pivetta. In a tightly contested game, the Padres edged out the Nationals with a final score of 4-3, thanks to Gavin Sheets scoring in the sixth inning after a timely ground-out by Jose Iglesias.

As the two teams clashed at Petco Park, the game showcased several betting trends worth noting. The Padres have a solid record at home against teams with losing records, winning 4 of their last 5 such matchups. The Nationals, however, are showing signs of life, covering the spread in 4 of their last 5 games. Expert analysts suggest leaning towards the Padres for the moneyline, while a bet on the over for the total runs scored is also advised.