As the San Diego Padres prepare to face off against the San Francisco Giants on June 2, 2025, both teams enter with contrasting recent performances. The Padres have won five of their last seven games, including a thrilling 6-4 comeback against the Pirates. Conversely, the Giants struggle with a 2-4 record in their last six games, despite a recent win over the Marlins. Stephen Kolek is set to pitch for the Padres, showcasing a 3-1 record and a 4.11 ERA. Meanwhile, Logan Webb will take the mound for the Giants, boasting a commendable 2.82 ERA and a 5-5 record.

This matchup is critical as the Padres look to extend their winning streak at Oracle Park, where Webb has shown promise with a 3-2 home record. The betting odds favor the Giants, with a moneyline of -175 against the Padres' +146. Our analysis suggests the best betting option may be on the over for the total runs at 7.0, reflecting both teams’ potential for offensive showcases.