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Go To Full MLB Digest
August 19, 2025
Giants vs. Padres Prediction, Odds, Probable Pitchers and Prop Bets for Tuesday, Aug. 19
Sean Treppedi
Sports Illustrated
Giants vs. Padres Prediction, Odds, Probable Pitchers and Prop Bets for Tuesday, Aug. 19

Padres host Giants at Petco Park with Nick Pivetta taking the mound after a season of elite strikeouts and solid run prevention, while Kai-Wei Teng looks to rebound from a rough prior start against San Diego. The night opened with a three-homer charge from the San Francisco lineup—Heliot Ramos, Rafael Devers, and Wilmer Flores—spotting the Giants an early cushion that San Diego could not fully erase. The betting edge leans toward the home club, who combine recent August splits against righties with a favorable park factor that boosts their lineup’s upside in fantasy lineups and daily bets.

Fantasy angles center on Pivetta’s high strikeout ceiling (7+ Ks in six of his last eight) and Teng’s shaky form, which could yield a short leash if the innings slip again. The Padres’ offense has shown life at home and against right-handed pitching, while the Giants’ reverse splits and early power provide potential for sneaky fantasy value from Ramos, Devers, and Flores if they stay hot. The Padres are favored to win, with the -1.5 line offering a slate-ready avenue for stacking Padres bats alongside Pivetta’s punchouts.

In DFS and betting terms, target Pivetta for strikeouts and a probably clean line, and consider Padres stacks if you expect Teng to yield loud hits early. Watch for late bullpen leverage and park-driven runs, which can swing a tight game in either direction. The Padres' home prowess and San Francisco’s occasional fatigue in this venue favor a smoother Padres win and a higher-probability pass for the -1.5 play.

With Pivetta on the mound, is a Padres win and -1.5 cover a solid bet in this matchup?Should fantasy managers fade Teng after his last poor outing, or still consider a speculative play?Which Giants hitters are the clearest bets to contribute in this series against SD’s right-handers?What is the optimal Padres stack approach for this game in DFS or a single-game slate?
Mentions:
@Heliot Ramos | San Francisco Giants | MLB
@Heliot Ramos | San Francisco Giants | MLB
@Kai-Wei Teng | San Francisco Giants | MLB
@Kai-Wei Teng | San Francisco Giants | MLB
@Nestor Cortes | San Diego Padres | MLB
@Nestor Cortes | San Diego Padres | MLB
@Nick Pivetta | San Diego Padres | MLB
@Nick Pivetta | San Diego Padres | MLB
@Rafael Devers | San Francisco Giants | MLB
@Rafael Devers | San Francisco Giants | MLB
San Diego Padres | MLB
San Diego Padres | MLB
San Francisco Giants | MLB
San Francisco Giants | MLB
@Wilmer Flores | San Francisco Giants | MLB
@Wilmer Flores | San Francisco Giants | MLB

https://www.si.com/betting/giants-vs-padres-predic..

San Francisco Giants:
Rafael Devers (38)
Osleivis Basabe (0)
Sam Huff (0)
Jose Butto (1)
Matt Gage (0)
Tristan Beck (1)
Hayden Birdsong (57)
Spencer Bivens (4)
Mason Black (13)
Kyle Harrison (146)
Sean Hjelle (32)
Trevor McDonald (0)
Erik Miller (31)
Robbie Ray (27)
Randy Rodriguez (4)
Landen Roupp (1)
Ethan Small (1)
Kai-Wei Teng (1)
Ryan Walker (62)
Logan Webb (260)
Keaton Winn (1)
Patrick Bailey (1)
Tom Murphy (3)
Matt Chapman (346)
Tyler Fitzgerald (94)
Wilmer Flores (0)
Marco Luciano (12)
Casey Schmitt (25)
David Villar (0)
LaMonte Wade Jr. (119)
Brett Wisely (9)
Jerar Encarnacion (16)
Jung Hoo Lee (6)
Luis Matos (9)
Grant McCray (16)
Wade Meckler (1)
Heliot Ramos (190)
Manager Bob Melvin (0)
Carson Ragsdale (1)
Carson Seymour (1)
Willy Adames (27)
Justin Verlander (7)
Carson Whisenhunt (9)
Christian Koss (3)
Drew Gilbert (2)