Week 21 closes the door to steady saves but opens multiple holds and bullpen plays. Dennis Santana remains the Pirates closer, with a chance at multiple save chances in a week. Jose A. Ferrer grabbed his first Nationals save and looks locked into late-inning work, even if not a high-volume shooter. Houston’s Bryan Abreu steps into the closer role while Josh Hader recovers, creating immediate fantasy value for saves. Randy Rodríguez lands in a true closer role with the Giants, and Phil Maton is the Rangers’ late-inning option, both solid adds in holds leagues and possible saves. Keegan Akin and Yennier Cano inherit ninth-inning chances in Baltimore, while Justin Topa and Cole Sands offer speculative saves in Minnesota. Michael Kelly and Sean Newcomb give Athletics and Boston some late-game leverage, and JoJo Romero and Riley O’Brien share ninth-inning duties for St. Louis. Kenley Jansen tops the saves leaders this week, with Matt Strahm handling holds for Philadelphia, and Detroit’s closer scene showing a committee with Kyle Finnegan and Will Vest. The Rockies’ bullpen era sees Seth Halvorsen in late-inning scenarios with potential saves, while Victor Vodnik lurks in the back of the bullpen. In short, plan for more one-off saves and a handful of holds as teams navigate post-deadline roles and injuries.