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Go To Full MLB Digest
August 18, 2025
Giants vs. Padres Prediction, Odds, Probable Pitchers and Prop Bets for Monday, Aug. 18
Iain MacMillan
Sports Illustrated
Giants vs. Padres Prediction, Odds, Probable Pitchers and Prop Bets for Monday, Aug. 18

The Padres clawed to the NL West lead, then watched the Dodgers smash that momentum with a three-game sweep, dropping SD two games behind again. Monday brings a pivotal series opener at Petco Park against the San Francisco Giants, a rematch of a season-long back-and-forth where San Diego has won 7-2 in their two meetings so far. The betting board favors SD by 1.5, with Robbie Ray taking the ball for SF and Nestor Cortés for the Padres. The Padres have surged offensively since the All-Star break, posting strong wRC+ and mounting pressure on SF’s pitching staff. Ray’s projected strikeouts are tempered by SD’s low strikeout rate since the break, fueling a popular UNDER 5.5 Ks bet. The Padres’ lineup, led by a lineup that includes Cruz, Soto, Machado and others, should test Ray early, while Cortés needs to minimize the damage and manage SF’s lineup to hand SD a necessary win.

Ray has posted decent, but not dominant, numbers against SD this season, and Cortés must prove he can lock in against a potent SD offense that sits among the league leaders in production since the break. Petco Park’s depth and bullpen depth will likely decide the opener, with SD hoping to regain momentum and re-establish a grip on the division race. This week’s action could reshape the NL West standings, making every series a pressure point for fantasy managers and bettors alike.

Which Padres hitters offer the best upside in this opener against Ray and Cortés?Is Robbie Ray under 5.5 strikeouts a strong value with Padres' plate approach?What is the best top-level bet in this Padres-Giants opener for fantasy bettors?How does Dodgers' sweep affect this week's NL West dynamics for fantasy bettors?
Mentions:
Los Angeles Dodgers | MLB
Los Angeles Dodgers | MLB
@Nestor Cortés | San Diego Padres | MLB
@Nestor Cortés | San Diego Padres | MLB
@Robbie Ray | San Francisco Giants | MLB
@Robbie Ray | San Francisco Giants | MLB
San Diego Padres | MLB
San Diego Padres | MLB
San Francisco Giants | MLB
San Francisco Giants | MLB

https://www.si.com/betting/giants-vs-padres-predic..

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