With a busy slate of MLB games on May 28, 2025, several players have emerged as promising candidates for home run prop bets. Aaron Judge of the New York Yankees continues to dominate with an exceptional season, boasting a near .400 batting average and a 22.9% barrel rate. His upcoming matchup against lefty Yusei Kikuchi, who struggles against right-handed hitters, presents a golden opportunity for a home run at +185 odds.

Cal Raleigh, the standout catcher for the Seattle Mariners, also makes waves with 19 home runs already this season. He faces Trevor Williams, a pitcher who has been vulnerable against left-handed hitters, making Raleigh's +230 odds appealing. Meanwhile, Gunnar Henderson of the Baltimore Orioles, despite a recent slump, has favorable matchups that could break his home run drought at +450 odds.

Longshots Ivan Herrera from the St. Louis Cardinals and Nolan Schanuel from the Los Angeles Angels are also on the radar. Herrera's impressive left-handed stats against Cade Povich and Schanuel's potential against Clarke Schmidt could deliver significant payouts, with odds of +950 and +1000, respectively. Betting on these players could yield substantial returns, especially given their current form and the circumstances surrounding their matchups.