This Wednesday's MLB slate includes a total of 11 games divided into two segments, starting with a 12:35 PM ET matchup and followed by a 6:45 PM ET set. Focusing on the night slate, pitchers are few and far between, with George Kirby ($9,900) leading the pack against a struggling White Sox lineup. Spencer Strider presents a stark contrast in matchup difficulty against the Brewers, which could sway decisions for fantasy managers.

Among mid-tier options, Michael Wacha ($7,400) and Dustin May ($7,200) stand out, with Wacha's better performance metrics offset by a challenging matchup. For value plays, Jeffrey Springs ($6,800) has demonstrated potential with an impressive strikeout rate and favorable matchup against the Nationals. Nestor Cortes ($6,900) returns after injury, but his performance remains uncertain against the Diamondbacks.

Top hitters to watch include Brent Rooker ($5,200) and Nick Kurtz ($6,100) from the A's, while Ketel Marte ($4,500) remains an interesting choice against left-handers despite his recent struggles. The Mariners and Padres feature as strong stacking options, thanks to favorable pitching matchups and recent offensive surges, making them enticing picks for DFS players.