The sixth week of the 2025 MLB season highlights critical two-start pitchers for fantasy baseball enthusiasts. Aaron Judge takes the top spot in the latest rankings, demonstrating exceptional performance so far. Amidst injuries affecting the rotations, teams like the Red Sox and Dodgers face uncertainty regarding their starting pitchers. Sean Newcomb is expected to step in for the Red Sox, while Ben Casparius looks to secure two starts for the Dodgers. On the other hand, the Twins’ Pablo López stands out with impressive stats, making him a must-start player. Cole Ragans and Seth Lugo are also favorable options, especially given their matchups against weaker teams.

Other pitchers like Nathan Eovaldi and Carlos Rodón should also be considered, despite tougher matchups, due to their current form. Streaming options include Tomoyuki Sugano and Edward Cabrera, both of whom offer upside in their upcoming starts. However, caution is advised with pitchers like Cade Povich and Sean Burke, who have shown inconsistency. Understanding these dynamics can significantly impact your fantasy league standings as the season progresses.