The San Francisco 49ers' recent draft picks reveal a strategic focus on fortifying their defense, particularly against the run. Mykel Williams, selected in the first round, is heralded as a high-floor edge defender, showcasing impressive traits that make him a safe bet for a successful NFL transition. His run defense grade ranks in the 97th percentile among college edge defenders, making him a standout choice for the 49ers.

In the subsequent rounds, the team added defensive tackles Alfred Collins and CJ West, both known for their strength and versatility. Collins, with an 85.0 PFF run-defense grade, is expected to make an immediate impact, while West offers promising potential as a rotational player. Meanwhile, the backfield faces competition for the secondary running back role following Christian McCaffrey's absence, with Jordan James emerging as a strong candidate due to his impressive PFF rushing grade over the last two seasons.

The Tennessee Titans have significantly revamped their linebacker unit this offseason, releasing all starters from the previous season and adding Cody Barton as the only new face. Returning players include Otis Reese, Cedric Gray, and James Williams, but the team is still searching for additional competition. In their pre-draft evaluations, the Titans have shown interest in various linebackers, including Northwestern's Xander Mueller, who attended the Tropical Bowl. Mueller's medical history, particularly his injuries from 2024, will be critical in determining his draft stock. Despite his lack of flashy athleticism, he demonstrated solid performance with 110 tackles, 10.5 tackles for loss, five sacks, and three interceptions in 2023. His versatility allows him to play both inside linebacker and edge, although he is expected to fit best in the middle in the NFL, where he can excel against the run.

The New Orleans Saints face a pivotal moment as they prepare for the 2025 NFL Draft, with various analysts suggesting different strategies to bolster the team. However, ESPN's Field Yates presents choices that many fans find troubling. At the ninth overall pick, Yates suggests drafting defensive end Shemar Stewart from Texas A&M, who has posted mediocre college stats, raising concerns about his potential success at the NFL level.

Conversely, Yates recommends a more favorable pick in Iowa State wide receiver Jayden Higgins at No. 40, known for his size and speed, which could help diversify the Saints' receiving corps. Additionally, he proposes trading up for Ohio State quarterback Will Howard, despite questions about the necessity of this move. Overall, Yates’ mock draft raises concerns about the Saints' decision-making and their ability to learn from past mistakes.

The waiver wire for Week 17 presents several intriguing options for fantasy football managers, particularly in light of injuries across various teams.

Jaylon Carlies of the Indianapolis Colts emerges as a top target if E.J. Speed remains sidelined. The Buffalo Bills also face defensive challenges, creating opportunities for players in linebacker and safety positions.

Other notable mentions include Owen Pappoe from the Arizona Cardinals and Jacoby Windmon of the Carolina Panthers, both of whom could see increased playing time due to injuries on their respective teams.

In Week 16, several players made significant impacts, including Kenny Moore with two interceptions and Taron Johnson and Marlon Humphrey both scoring pick-sixes. As Week 17 approaches, a list of waiver wire adds is presented, featuring 13 defensive players who could bolster fantasy teams for championship games.

Highlighted players include Jamien Sherwood of the New York Jets, Darius Muasau from the New York Giants, and Dee Winters of the San Francisco 49ers. The article also discusses potential streaming options for defensive linemen and backs, emphasizing matchups against the sack-prone Cleveland Browns.