Five wide receivers have a real shot at finishing as fantasy football’s overall WR1 this season. Ja’Marr Chase sits as the clear favorite, with Justin Jefferson and CeeDee Lamb close behind in the ADP mix. The group also features Nico Collins and Brian Thomas Jr. who flashed late-season upside, plus Drake London and Marvin Harrison Jr. who carry high ceilings in new or improved offenses. The real wild cards are how playing time, QB fit, and injuries shape their year-to-year trajectories, making each of these players a bold spring target in drafts.

Nico Collins has transformed into a high-quality target for Houston, boosting his per-route efficiency and keeping his fantasy floor steady when healthy. Brian Thomas Jr. carved out a near-every-down role in Jacksonville late in 2024, finishing with productive final stretches. London shifted into a slot-heavy, high-target-rate role for Atlanta, hinting at a breakout path with Penix Jr. stepping in. Harrison Jr. in Arizona offers top-end upside if Murray- Coen unlock timing and chemistry, while Puka Nacua’s late-season surge with the Rams demonstrated breakout potential even amid quarterback flux.

ADP has these receivers clustered in early-to-mid rounds, underscoring the fantasy bet: if everything clicks—health, quarterback chemistry, offensive system—these names can deliver elite WR seasons. Managers drafting with a blend of upside and risk will want exposure to Chase, Jefferson, Lamb, and the rest as potential league-winners, while preparing contingency plans for injury and shifting target shares throughout the year.