Week 2 WR starts lean into ceiling plays such as Pickens against a vulnerable Giants secondary, Tillman exploiting Ravens’ man-heavy looks, and Higgins aiming to rebound after Week 1. Kupp presents a high-variance path given Seattle’s offense and injury risks. Ridley is a potential fade with Cam Ward’s uneven start in Tennessee. Lawrence and Stroud anchor a QB landscape that amplifies receiver ceilings, while Darnold’s Seahawks expose a path for opportunistic WRs. Two bold sit-start arcs emerge for Week 2 in this breakdown.

Week 2 fantasy WR rankings spotlight a star-studded core and broad depth, led by Lamb, Chase and Jefferson, with Nacua pushing for WR1-level floors. Downticks for boom/bust options like Williams sit beside strong midrange bets from St. Brown, Collins, and London. Injury chatter—London back in full, Wan'Dale Robinson questionable—adds pivot potential. Depth makes close start-sit calls critical in PPR formats as roster construction leans on high-floor plays with ceiling upside.

Key piece-by-piece notes include JSN’s Week 1 chemistry translating into a favorable Week 2 date for Seattle, Moore’s upside versus Detroit, and Waddle’s health status shaping decisions in a divisional slate. The article emphasizes the WR pool’s breadth and urges ongoing updates through the week for optimal Week 2 lineup construction.

Week 2 fantasy QB rankings for 2025 spotlight the same mix of elite ceiling and plus-matchup upside that fantasy managers crave. Justin Fields’ rushing floor keeps him in QB1 territory, while Caleb Williams anchors a high-upside Bears offense as a top weekly option in Superflex. Mac Jones enters with a favorable Saints test, and Patrick Mahomes faces a stiff challenge in a rematch against Philadelphia. J.J. McCarthy and Michael Penix Jr. sit as strong Superflex plays, with several veterans and youngsters rounding out the top tiers.

The Week 2 outlook emphasizes risk-reward: injuries and known blockers shift the value of several signal-callers, from Purdy’s out to Mahomes’ matchup dynamics, shaping lineup decisions for fantasy managers who need big weeks from their QBs to carry squads into the weekend.