Week 1 injury designations shape depth charts for Lions and Packers heading to Lambeau. Detroit has three players ruled out and seven on the questionable list, with Jamarco Jones, Trevor Nowaske and Sione Vaki officially out and Jones moving to IR. Giovanni Manu is one injury away from possible offensive action, and Detroit added Jacob Saylors to the active roster with Anthony Pittman elevated. Green Bay carries seven questionable names, including Micah Parsons, Zayne Anderson, Nate Hobbs, Jayden Reed, Dontayvion Wicks, Savion Williams and Barryn Sorrell, with Reed managing a Jones fracture and Parsons’ snap count expected to be limited.

Fantasy angles tilt toward Parsons’ limited workload and Reed’s status, while Manu could see a small Week 1 chance if Jones remains out. The Lions’ special teams take a hit with Nowaske and Vaki out, and Detroit will lean on the depth pieces stepping in for Week 1. Stay plugged into late-week updates for any shifts in designation that could unlock or cap fantasy upside.

Detroit Lions open Week 1 with Jamarco Jones on IR, narrowing their tackle depth as they prep to face Green Bay. Gio Manu could make his debut, potentially sliding into a starting or heavy-rotation role to bolster both pass protection and run blocking. The matchup at Lambeau tests the Lions’ reshuffled line and will influence early-season blocking schemes and fantasy implications for the unit and backfield.

Fantasy emphasis centers on how Manu’s status and the absence of Jones shape Detroit’s protection, play-action timing, and run design. If Manu steps up, expect more stability on the edge and a possible uptick in efficient rushing attempts and targeted play-action looks against a Packers defense known for edge pressure in Week 1.