Detroit’s preseason injury wave reshapes fantasy expectations. Levi Onwuzurike’s season-ending ACL and multiple Players on PUP/IR thin the defense’s interior and depth. Alim McNeill and Malcolm Rodriguez started camp sidelined, Miles Frazier on reserve/IR, Ennis Rakestraw Jr. and Dan Jackson among those shelved, with Ahmed Hassanein waived after an injury settlement. Colby Sorsdal, Justin Herron, and Kenny Yeboah also land on IR; Amon-Ra St. Brown remains the primary offensive engine, but early depth tests could push other Lions into bigger roles.