Detroit Lions sit at +1100 to win the Super Bowl on FanDuel as the 2025 season looms, with Chiefs, Eagles, Bills and Ravens ahead in the betting order. The Lions’ brain trust, Dan Campbell and Brad Holmes, tout a deep, healthy roster after a season plagued by injuries, including Ennis Rakestraw and Levi Onwuzurike. Green Bay’s all-in push and talk of Micah Parsons entering the mix add intriguing drama to a crowded NFC landscape. Odds updates are fluid, and rosters are still being tinkered with as camp hits full stride.

Fantasy-minded observers should watch Lions depth pieces who could emerge if held back by injuries, plus how the Packers’ bold moves reshape the defensive talent pool around Parsons. The narrative also reinforces big-picture bets: top contenders like Kansas City, Philadelphia, Buffalo and Baltimore remain viable paths to a title, while the Lions’ upshot hinges on roster health and midfall developments that could nudge fantasy values across multiple positions.