Rams injury news heightsen Week 2 suspense: Dotson and Avila are listed as week-to-week with ankle sprains, Havenstein’s status is uncertain but likely to play, Parkinson finished the game despite an AC sprain, and Beaux Limmer may be leaned on if depth is needed. Adams is noted as a rest-day participant but expected to play. The Titans also roll through a shifting line with Diggs and Latham out and Key/Sneed limited.

Fantasy angles center on the interior line health for Los Angeles and the edge presence for Tennessee. If Dotson/Avila are limited, Rams run and pass protection could wobble, elevating the value of Rams’ depth pieces; conversely, Cam Ward’s early pressure opportunities could swing quick scores for Tennessee.

Ultimately, the trench duel may decide the outcome. Monitor Dotson, Avila, Parkinson, and Adams for Rams shifts, and Arden Key plus Cam Ward for Titans optimism and potential fantasy upside in a high-variance Week 2 showdown.

Denver and Tennessee open Week 1 with intrigue around Cam Ward and a retooled Titans defense. Ward’s limited preseason looks are framed as high ceiling, low risk, giving fantasy managers a speculative kitchen-sink option if he starts and leans on efficiency over volume.

Meanwhile, Tennessee stacked pressure with Dre’Mont Jones and Arden Key, with Roger McCreary sharpening a top-tier pass defense and Cedric Gray emerging in the middle. Denver must navigate the air and altitude while Ward grows into a franchise-altering signal-caller, creating a dynamic, high-variance fantasy matchup.

Denver opens at Mile High against Tennessee with Bo Nix under center, testing a Broncos offense that aspires to surge after a rookie-year breakout. Tennessee linchpin Jeffery Simmons publicly challenged Nix’s pace and reads, setting up a Week 1 chess match on the edge of the pocket. Coach Sean Payton pushed back, signaling a growth-driven, more nuanced approach to Nix’s mobility and timing. Expect Denver to lean into a stronger O-line and deliberate rhythm to start the season.

Fantasy managers should watch for Nix’s rushing ceiling and how quickly Denver implements bootlegs and play-action to unlock the offense. If the line holds and Nix keeps decisions clean, Denver’s early-game scoring potential could rise, shaping Week 1 fantasy projections for multiple Broncos pass-catchers and the run game.

Five notable fantasy contributors open the season on the PUP list: Brandon Aiyuk, Christian Watson, Tank Dell, Taysom Hill, and Deshaun Watson. Aiyuk targets Week 6 for a 49ers return, Watson will miss at least four, Dell is ramping up from a knee injury, Hill remains an offensive weapon despite ACL rehab, and Watson’s Browns tenure looms as a potential late-season spark. Early weeks demand patience but the upside for the stash-able stars remains elite once they’re back on the field.

With DFS and redraft rosters in flux, savvy managers balance short-term voids against long-term upside. Aiyuk’s return could re-establish a top-3 SF receiving dynamic, Watson’s midseason reentry could unlock Cleveland’s aerial game, and Hill’s gadgetry remains a fantasy lever once fully healed. Dell’s timetable keeps Texans’ pass game in flux, making dynasty and hold-or-stash moves essential in shallow leagues.

Van Jefferson led Tennessee’s offense with the top PFF grade in the 23–13 preseason win over Minnesota, illustrating polished route-running and reliable hands as Cam Ward steered the offense. The OL trio of Skoronski, Udoh and the TE duo of Whyle and Okonkwo contributed key plays, hinting at depth behind Burks. On defense, Simmons and Gaziano anchored the rush, while Ward and Amari Burney highlighted special-teams contributors Mullings and Whyle.

Overall, the Titans flashed potential across units, with Jefferson signaling a real ceiling as a Week 1 option, and the defensive line showing enough disruption to bolster IDP intrigue ahead of roster cuts.