Geno Smith's Raiders tenure hits turbulence as Las Vegas is blasted by Indianapolis 40-6 in Week 5. Smith throws two more interceptions, bringing his total to nine in five games—the most by a Raiders quarterback through five games since Jim Plunkett in 1982.

Despite a two-year, $75 million extension, the offense remains boxed in by turnovers and rust. Fantasy managers must reassess Smith and the supporting cast as the Raiders chase a turnaround.

Colts-Raiders Week 5 injury report reshapes fantasy usage. Alec Pierce is out with a concussion. If AD Mitchell’s playing time isn’t guaranteed, Ashton Dulin could step in, creating volatility at the Colts’ X/slot roles. Kenny Moore is out; Mekhi Blackmon likely starts outside, with Tyquan Lewis questionable and rookie JT Tuimoloau stepping in if he can’t go. Daniel Scott is out, thinning the Colts’ secondary.

Raiders’ tight ends Brock Bowers (knee) and Michael Mayer (concussion) sit at the edge of game status, while Eric Stokes (knee) is also questionable. If Bowers sits, Mayer may command more targets; if active, Vegas leans on a short-to-intermediate attack. Inactives arrive 90 minutes before kickoff, so late-week updates will drive final fantasy decisions.

Colts cornerback Xavien Howard has retired and been placed on the reserve/retired list, opening an outside-corner vacancy just before Week 5. Indianapolis signed Trey Washington from the practice squad to the 53-man roster to fill the spot. Howard started for Indy this season but has been targeted heavily in two of four games, including a 112-yard, TD outing against the Rams. The team will evaluate options, with Mekhi Blackmon or Johnathan Edwards as likely next men up.