McCarthy is out with a right high ankle sprain, sidelining him for a third straight game, so Carson Wentz will start Sunday for Minnesota against Cleveland in London. The Vikings’ offense is thin up front with multiple linemen out, forcing a reshuffle: Brandel to center, Huber at left guard, Skule at right tackle, and Darrisaw back after Week 3. Fantasy managers must weigh Wentz’s ceiling against the shaky line in a high-stakes London tilt.