Week 2 of 2025 delivered a wave of fantasy busts across QB, RB, WR and TE, forcing managers to rethink lineups and smartly pivot for Week 3. Michael Penix Jr. and J.J. McCarthy faltered in prime time, while a host of running backs—Henry, Hall, Charbonnet, Pacheco, Hunt and more—never found their footing. WRs like A.J. Brown, Marvin Harrison Jr. and Drake London cooled after strong openings, and tight ends such as Mark Andrews and T.J. Hockenson offered limited fantasy returns. Bounce-back potential remains for several, but risk has clearly risen across the board.

Rosters should shift toward safer floors and clearer use-cases in Week 3, with attention to upcoming matchups against softer defenses and potential in-game script shifts. The busts spotlight several buy-low windows, particularly at WR and TE, where targets and red-zone usage could swing dramatically with a favorable game plan. Fantasy managers should weigh the rest-of-season trajectory against Week 2 volatility and adjust accordingly.

Overall, Week 2 underscored the value of depth and matchup-fueled decisions. Staying ahead requires identifying hidden Week 3 opportunities among RBs with clearer roles, WRs in jam-friendly offenses, and TEs who still command a red-zone presence despite rough Sundays.

Philadelphia’s passing attack must improve quickly after Hurts’s 101-yard day against Kansas City, finishing with 94 net passing yards due to sacks. Brown and Smith weren’t enough to unlock a high-octane aerial game, and the staff must scheme open looks rather than relying on improvisation. Patullo’s play-calling and Sirianni’s decisions are under scrutiny as the offense adapts. On defense, Mukuba and Campbell highlighted the rookies, while Vic Fangio’s adjustments kept Philly competitive. The 2-0 start remains intact, but the path to explosive weeks is clear.

Philly travels to Kansas City for Week 2 in a high-stakes rematch, with the Eagles bringing a potent, multi-pronged attack and the Chiefs facing injury-adapted WR depth. Worthy’s shoulder and Rashee Rice’s suspension thin KC’s arsenal, nudging the spread toward Philadelphia and putting more pressure on Mahomes to improvise.

The Eagles’ front will test a banged-up KC offense, while Vic Fangio’s defense aims to keep the Chiefs in check. Fantasy angles lean heavy on Philadelphia receivers, with the team predicted to press early and often. Final score: Eagles 31, Chiefs 20; Best Bet: Eagles -1.5.

Watch for line movement and matchup-driven props, especially on Brown and DeVonta Smith, as Philly looks to exploit KC’s depth and keep the crowd momentum in their favor.