End-of-preseason spotlight on Penn State alums in the NFL shows Barkley, Dotson, Freiermuth, Ji’Ayir Brown and other Nittany Lions landing on prominent 53-man rosters, signaling a strong fantasy foothold for PSU in 2025. Injury notes touch Adisa Isaac’s elbow and Yetur Gross-Matos’ status, while Adisa Isaac is sidelined until midseason and Kevin Givens begins the season on IR. Standout performers Barkley, Godwin, Warren and Carter anchor the PSU pipeline in meaningful fantasy context.

Across the league, PSU colors appear from NYG to PHI, PIT and SF, underscoring depth and opportunity for fantasy managers. As rosters settle, the PSU connection remains a compelling angle for late-draft value and potential breakout runs this season.