Mahomes faces tighter pressure and shorter windows as the Chiefs’ attack adapts to injuries and a new-look line. Philadelphia’s improved edge rush and potential quarterback spy loom large in Week 2, with explosive plays and own-ball control swinging the outcome.

Philadelphia leans on a sharper rush plan and a more disciplined approach to limiting big plays, while KC must sustain drives and find rhythm with new receivers out. Fantasy angles hinge on Mahomes’ efficiency, Hurts’ handling of pressure, and which supporting cast members step up for both sides.