Week 1 injury news shapes fantasy lineups: Tanner McKee is ruled out for the Eagles, elevating Sam Howell as the top backup behind Jalen Hurts, with Kyle McCord as a potential practice-squad elevation. Landon Dickerson returns at left guard after a back scare, Sydney Brown starts at safety, and Jalen Carter is a full-go, with Nakobe Dean eligible to return after Week 4. On the Cowboys side, Perrion Winfrey is out, while Trevon Diggs and Tyler Guyton are cleared to play after full practices, and Payton Turner is involved in the depth chart. These shifts hammer QB depth, run-game dynamics, and pass-defense depth for Week 1.

Bottom line: the Eagles rely on Hurts with limited McKee availability, while the Cowboys lean on Diggs’ return and a fuller defensive front. Fantasy players should target backup QB scenarios, Eagles’ offensive line stability, and Cowboys’ defensive rotations, as those dominoes will determine hinges in DFS and season-long rosters.