Two Steelers on Wednesday's injury report—Derrick Harmon (knee) week-to-week and out for Week 1, Cory Trice Jr. (hamstring) DNP with Week 1 status unclear, and Nick Herbig (hamstring) limited and questionable. Depth at defensive line and cornerback is tested as Pittsburgh opens vs. the Jets. Fantasy players should monitor late-week updates for potential snaps and streaming options.

Harmon's absence could nudge the defensive line rotation, while Trice's hamstring adds uncertainty to Pittsburgh's2ndary depth. Herbig's status could influence edge-rush reps. In Week 1 against New York, these moves may tilt opportunities for Steelers sleepers and Jets playmakers in deeper formats as practice reports finalize rosters.

Campbell seizes Detroit's LB1 role, bringing massive tackle upside and a true full-season workload for 2025. Bosa is positioned to reclaim elite sack production as the 49ers’ premier pass rusher, with weekly upside in a favorable schedule. Henley steps into a true full-time linebacker role with the Chargers, benefiting from a zone-heavy defense that should elevate his tackles and big plays. Elliott projects to a box-heavy safety role in Pittsburgh, likely delivering high tackle totals, while Turner emerges as a durable, high-usage defensive tackle for the Rams with both sack and tackle upside.

Dallas faces a rough two-game preseason start as Brian Schottenheimer pushes for a cleaner, more physical attack. The offense stalled to two touchdowns while amassing 199 rushing yards, and Joe Milton III completed just 55.3% of his passes. The defense surrendered ground gains and Dallas fell short on third downs (6 of 22). The starters won’t play until September, so the depth and scheme repeats will be tested again in the finale against Atlanta as Milton works on footwork and grip. Dallas is not in panic mode, but improvement is needed before Week 1.

Third-down conversion and run-game consistency are at the center of the critique, with Schottenheimer admitting play-calling and tackling as culprits. Positive notes emerge on Tyler Booker, Princeton Fant, James Houston, and Mazi Smith, plus the work of slot corners Kemon Hall and Zion Childress. The plan is to finish strong in practice and build speed and physicality for the regular season.

No. 21 on the Steelers carries a rich legacy. The 2025 wearer is Chuck Clark, a veteran safety who joined Pittsburgh after time with Baltimore and the Jets, providing steady depth behind Juan Thornhill and DeShon Elliott with potential starter value if called upon. The countdown traces the jersey through five Steelers to wear 21 in recent years (Clark 2025–present, Darius Rush 2023–2024, C.J. Henderson 2024, Tre Norwood 2021–2022, Sean Davis 2018–2020), and crowns Chuck Cherundolo as the franchise’s best No. 21—a Pennsylvania native who earned two Pro Bowls and a Second Team All-Pro in the 1940s and was enshrined on the Steelers Legends Team. The Jets game at MetLife Stadium provides the stage where this jersey’s story keeps growing, and fantasy managers should watch how Pittsburgh deploys 21 in base vs. nickel and how depth at safety could produce streaming opportunities in weeks 1–4.