Derrick Harmon’s first NFL preseason ends early with a right knee sprain, and Pittsburgh coach Mike Tomlin labeled it week to week after an MRI. The Steelers are hopeful for a September return, but the injury tests their interior DL depth, likely elevating Isaiahh Loudermilk and Yahya Black as the next options. The Panthers’ Raheem Blackshear enters the backdrop as a contrasting run-game note while Harmon focuses on rehab and regaining field time before Week 1 vs. the Jets.

Derrick Harmon’s knee sprain is being treated as week-to-week after an MRI initially pointed to four-to-six weeks, easing fears of IR. Yahya Black is poised to fill in short-term, while Daniel Ekuale and Isaiahh Loudermilk provide interior DL depth for a potential 53-man roster tweak. A Week 2 return against Seattle is possible, with Week 1 vs. the Jets likely out. Fantasy angles center on Black’s immediate snaps and the deeper DL rotation becoming viable.

Pittsburgh’s injury update shapes roster decisions and game-plan leverage early in the season. If Harmon stays on a gradual timeline, Black could become a quick add, with Ekuale and Loudermilk offering value if Harmon’s recovery stalls. The Seahawks game in Week 2 looms as the first real stress-test for the defense without Harmon.